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Published in-vitro work commonly uses GHK-Cu at concentrations between 10 nM and 10 M in fibroblast culture, with 1 M representing a frequently reported working concentration

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(2012) 14:e1

Rare risks include copper toxicity, particularly in individuals with underlying conditions such as Wilsons disease (a genetic disorder causing copper accumulation), and theoretical concerns regarding angiogenesis promotion in the context of active cancers
