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Proton electrochemical gradient: driving and regulating neurotransmitter uptake

Similarly, S-allyl cysteine (SAC), an organic sulfur compound derived from garlic, demonstrates broad antioxidant and immunomodulatory effects by lowering ROS levels and inhibiting pro-inflammatory cytokines (e.g., IL-6 and myostatin), thus alleviating muscle atrophy (89)

These elements support the relation between this condition and systemic inflammation, due to the ethanol-mediated activation of nuclear factor-B (NF-B) signaling pathway, which could alter gut barrier integrity, increasing portal and systemic endotoxemia

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