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Studies have found that under pathological conditions, astrocytes are activated by A to produce cytoinflammatory factors, complement, oxygen free radicals, etc., which then trigger inflammation, promote nerve cell damage and death, and ultimately aggravate Alzheimers disease (Matuszyk et al., 2021)

In other words, while subtle gene expression changes may occur under low-dose conditions, these did not lead to noticeable physiological or developmental abnormalities due to potential compensatory mechanisms in the body or insufficient activation of downstream effectors

Tomosugi N, Yamamoto S, Takeuchi M, Yonekura H, Ishigaki Y, Numata N

J., Meka, S