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ME/CFS have a wide range of alterations affecting glycolysis, TCA cycle, diverse amino acid pathways, purine, pyrimidine, sphingolipid and phospholipid pathways that imply dysfunction of mitochondrial and microbiome metabolism 14,15,16,17,18

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CB-839, a GLS inhibitor that blocks the conversion of glutamine into glutamate, reduced the production of R-2-HG in AML cell lines and patient tissues harboring IDH1/2 mutations 123

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[DOI] [PubMed] [Google Scholar] 283.Chen BC, Yu CC, Lei HC, Chang MS, Hsu MJ, Huang CL, Chen MC, Sheu JR, Chen TF, Chen TL, et al

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Moreover, RT increased handgrip strength by 28.4%, fat-free mass by 4.1%, hemoglobin by 5%, iron by 33.4%, glutathione by 121%, and Trolox equivalent antioxidant capacity by 14.2% ( p 11g

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