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13,46 Intensive glycemic control significantly reduces the incidence and progression of neuropathy in T1DM and T2DM patients
This study is limited by the heterogeneous interventions, dose regimes, limited sample sizes and evaluation methods which hindered the possibility of an objective statistical analysis
Some studies have shown that various stimuli, including hypoxia, cytokines, chemokines, thrombin, LPS, DAMPs and apoptosis, can lead to the activation and damage of ECs (94,95)
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