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[Abstract]2025 Mar 29:154:114528

Protein Cell (2020) 12:599620
It has been determined that when glutamine depletion activates the energy stress AMPK pathway and inhibits mTORC1 activity, this results in the subsequent inhibition of the protein expression level of -TrCP, consequently leading to abnormal cell cycle progression and reduced proliferation [19]

Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance