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indicating in the subject the concerned Advisory, or call (02) 8857-1900 local 8105 and 8112

Information sources and search The literature was explored using the MEDLINE (via PubMed) and Web of Science databases, including all articles published from the inception up February 2020

The degree of heterogeneity across the results of different studies was quantitatively assessed by the I 2 statistic, with I 2 50% indicating substantial heterogeneity [11]

It is not a true vitamin because it is also biosynthesized endogenously from dietary amino acids (methionin, lysine), especially in the liver and in the kidneys [29, 30]