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You can't just give someone massive doses of EPO for nerve pain because it would thicken their blood to dangerous levels
Glutathione has been shown to protect B12 from degradation by pollutants, increasing its availability for the continuation of the methylation reaction (Watson)

306 In an ALD model, a Bacteroides acidifaciens strain isolated from the gut of gentamicin-treated mice was confirmed to reduce CD95/CD95L-mediated hepatocyte apoptosis by inhibiting hepatocyte surface CD95 expression, thereby exerting protective effects against both Concanavalin A- and alcohol-induced liver injury

K., Gay, R