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Additionally, in the context of lowered ATP production, which is a hallmark of mitochondrial diseases, it is important to note that NAC, essentially only being a form of cysteine, will require 2 ATP molecules to be converted to glutathione

doi: 10.1016/s0140-6736(73)91602-4

By doing so, the recorded events are specifically induced by the substance, rather than being a result of overall cytotoxicity and cell death (Rodrigues et al., 2018
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Total Glutathione Determination and Oral Supplementation It makes good sense to aim for the highest values of total glutathione for maximum protection and also to ensure that the selenium level is optimal
