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Mild gastrointestinal symptoms have been reported in some cases
Clinical trials investigating obesity used these dosing ranges with favorable safety outcomes
doi: 10.1113/expphysiol.2013.073163 24 BolignanoDCabassiAFiaccadoriEGhigoEPasqualiRPeracinoAet al
The metabolic benefits extend to cellular energy regulation, where NNMT inhibition increases intracellular NAD+ levels by 1.2-1.6 fold
