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Interleukin-12 inhibits development of ectopic endometriotic tissues in peritoneal cavity via activation of NK cells in a murine endometriosis model

For further information, see some of the following papers Qualitative Differences in Protection of PTP1B Activity by the Reductive Trx1 or TRP14 Enzyme Systems upon Oxidative Challenges with Polysulfides or H2O2 Together with Bicarbonate, Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades and Control of protein function through oxidation and reduction of persulfidated states

Hofstee P, McKeating DR, Bartho LA, Anderson ST, Perkins AV, Cuffe JS (2020) Maternal selenium deficiency in mice alters offspring glucose metabolism and thyroid status in a sexually dimorphic manner

thus, the phenotype is manifest fully in males whereas female heterozygotes display varying degrees of G6PD deficiency, due to alternate X-chromosome inactivation 3,4