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Description
Glutamine depletion decreases the expression of tight junction proteins in the gut and may increase intestinal permeability (when toxins from the gut can leak into the bloodstream), which can trigger the type of chronic, body-wide inflammation that underlies many metabolic disorders
Serum APAP and liver enzyme levels (AST/ALT) should be obtained as soon as possible
Cecal ligation and puncture: the gold standard model for polymicrobial sepsis

Rasmussens syndrome treated with anakinra
