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This is crucial for ensuring that muscle and cardiac tissue heal with flexibility rather than stiff, non-functional scar tissue
We find that ArfGAP1 proteins containing residues 137415 and 252359 are robustly phosphorylated by G2019S LRRK2 and to a lesser extent by WT LRRK2, relative to kinase-inactive D1994A LRRK2 or in the absence of LRRK2 (Figures 1C,G)
Bioactive insulin-like growth factor-I in obesity
