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cerevisiae , in which GPP1 and GPP2 encode very similar proteins, that have the same catalytic function, but are differentially regulated according to the environmental condition (Pahlman et al., 2001)

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This could also be the case for some mitochondrial proteins like Complex I and Odh which seem to be quite sensitive to S-glutathionylation (Beer et al., Enzymatically driven protein S-glutathionylation reactions It has long been known that cytosolic thiol oxidoreductase glutaredoxin-1 (Grx1) catalyzes the deglutathionylation of cytosolic proteins (Mannervik and Axelsson, 1980)

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