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By deepening our understanding of the molecular mechanisms by which Pb impairs glutamatergic signaling, we can better inform strategies for prevention, remediation, and neuroprotection, ultimately safeguarding brain health across the lifespan

First, cysteine is conjoined with glutamate through the action of glutamate cysteine ligase to produce gamma-glutamylcysteine, which proceeds to link with glycine via glutathione synthase [48]

10.1016/S0140-6736(14)60456-6 46 NeuhausA

Molecular mechanisms of ferroptosis and relevance to inflammation
