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EFFECT OF OCM NUTRIENTS SUPPLEMENTATION ON GLUCOSE METABOLISM INDICES Emerging evidence indicates that the etiology of HHcy may also involve genetic variation encoding key enzymes of OCM, which may contribute to diabetes development [6,13]

IL-6, aside from its proinflammatory cytokine activity, may also cause an increase in BBB permeability, contributing to its disruption and further immune cell infiltration in CNS (93)