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So, we decided the study design be based on the pre-post intervention model

28 Lumacaftor (200 mg) + ivacaftor (125 mg), Orkambi, is the first approved (2015) CFTR corrector and potentiator combination therapy

Additionally, while the most common side effect was mild to moderate gastrointestinal upset, there were fewer events per 100 patients across all of the cagrilintide treatment groups in comparison to the subjects receiving 3.0 mg of liraglutide [1]

W., DeRidder L., Sanjurjo L