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Cellular Migration & Repair: Explored for combined activity in upregulating actin sequestration (cell motility), modulating inflammatory markers, and accelerating overall wound closure in vitro
Long-term safety data for subcutaneous injection is limited
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Thus, FOXO4-DRI targets high SASP-expressing senescent cells that have naturally developed in the kidneys of fast aging Xpd TTD/TTD mice and in doing so restores kidney homeostasis
