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Its regulation is also different from that of NRF2, which is mainly regulated by N-glycosylase 1 (NGLY1) and DNA loss inducer 1 homolog 2 (DDI2) [13, 14]
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Possible mild and temporary side effects include: Warmth or flushing Mild nausea Injection-site discomfort Rare allergic reactions Patients are monitored during treatment
Ou P, Tritschler HJ, Wolff SP (1995) Thioctic (lipoic) acid: a therapeutic metal-chelating antioxidant