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Consistently, NMR analysis revealed elevated levels of glutamine and serine, accompanied by decreased concentrations of the glutamic acid precursor -ketoglutarate in PD patients, while UPLC/MS analysis indicated a reduction in serum glutamic acid levels (Figs

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The European Federation of Neurological Societies guidelines on neuropathy recommend pregabalin, gabapentin, duloxetine, tricyclic antidepressants, and venlafaxine for first-line treatment, with opioids and tramadol reserved for second-line therapy [37]

Golden oyster mushrooms, apart from containing immune-supporting beta-glucans, contain some of the highest amounts of ergothioneine