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From a research perspective, at least three medium-term priorities appear particularly important
Therefore, one may expect that fever in old rats, whose basal body temperature differs from that observed in young rats, changes
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However, in HCC, its sustained activation acts as a double-edged sword: rather than acting solely as a cytoprotective factor, NRF2 facilitates tumor survival, proliferation, and resistance to treatment by preventing ferroptotic cell death and enabling metabolic reorganization [49, 50]
