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U.1993Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen (I) gene expression in human liver fat-storing cells

In addition to these environmental factors, other population differences, such as linkage disequilibrium of the GPx-1 locus with other specific modifying genes, the influence of other gene variants that act to modulate GPx-1 activity [such as the SelP subtypes mentioned above (252)], and/or the presence of other gene variants that act in concert with GPx-1 to modify disease risk may also explain differences among studies performed in different populations

In two patients, empty sella was detected on MRI, but this finding was considered a normal variation