drug causes cysteine starvation glutathione depletion mrc-5 Pyroglutamic acidosis Regulators of the transsulfuration pathway
Description
We found that DEM 1 mM induced death in 4 day old adult worms (at the end of their reproductive phase) in a dose- and time-dependent manner, with 50% lethality occurring after 24 hr exposure to 10 mM DEM (Figure 1A) associated with 50% depletion of glutathione (Figure 1B)
Sikiric, and S
Thus, medical staff use this type of syringe for a long time
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