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In this review, we discuss intracellular sources of ROS, the role of oxidative stress in heart disease, evidence linking mitochondrial ROS to cardiac disease, the efficacy of ROS-based therapeutics in the heart, and the emerging frontier of mitochondria-targeted antioxidant therapies and their application to cardiac disease

Disinhibition of somatostatin-positive GABAergic interneurons results in an anxiolytic and antidepressant-like brain state

When circumventing responses to pathogenic infections such as coronaviruses, a healthy gut microbiome may be vital to maintain an optimal immune system, preventing a cascade of excessive immune responses that ultimately damage the lungs and vital organ systems (Figure 1)

assessed the involvement of PLA 2 and SMase in the molecular pathways leading to oxidative stress-induced eryptosis in workers exposed to lead
