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Only randomized trials contributed to quantitative synthesis

Shannon CE, Ghasemi R, Greenhaff PL, Stephens FB

To advance translational applications, future studies should focus on: (1) transforming dynamic biomarkers into clinical decision-making tools, such as evaluating early changes in circulating mitochondrial-derived vesicles or oxidative stress markers (e.g., 8isoprostaglandin F2 (8-iso-PGF2))to predict subsequent biochemical and histological responses

doi: 10.1016/s0272-6386(03)00110-0
