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While WADA provides the framework, individual federations may have additional requirements or enforcement mechanisms

The following criteria were considered: Full economic evaluations: cost-utility analysis, cost-effectiveness analysis, cost-benefit analysis Economic evaluations reporting incremental cost-effectiveness ratios (i.e., cost per quality-adjusted life year/life years gained or cost per event avoided) Studies in patients with confirmed vitamin B12 deficiency Studies in English Abstracts were reviewed by a single reviewer and, for those studies meeting the eligibility criteria, full-text articles were obtained

Methylene blue has been safely used in humans for over 100 years, with a fascinating story of how scientific curiosity led to numerous medical breakthroughs

Glutathione is an antioxidant that is naturally found in the body and is made up of three amino acids: glutamine, cysteine, and glycine