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By regulating tight junction proteins, polyphenols serve to strengthen the integrity of the intestinal barrier and avoid the "leaky gut" disorder that frequently leads to dysbiosis (Islam et al., 2023)
There are other cancer cells inducing cachexia, such as melanoma B16 and adenocarcinoma MAC16, but they have been far less explored ( Compared to cancer cell inoculation, genetic models, such as APC Min/+ and KPP (K-Ras
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