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Description
Owing to oxidative damage, multiple covalent bonds in the DNA get modified, including inter and intra-strand crosslinks, strands collapse, crosslinking between proteins and DNA occurs, lesions form in single nucleobase, etc
Major antioxidant systems in skeletal muscle It is crucial for a cell to sustain redox homeostasismaintain ROS below a threshold level and keep their function as a signalling molecules, while reducing their toxic effects (Barbieri and Sestili 2012)
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