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As mentioned, 1 -ARs display agonist-induced downregulation chiefly due to decreases in mRNA levels (Liu et al., 2019
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Several studies have reported the potent antifungal effects of essential oil nanoemulsions against pathogenic fungi, such as Candida species, Aspergillus species, and Cryptococcus neoformans , which are common causative agents of invasive fungal infections 81,82
