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As indicated above, NADP + can be generated via the action of cytoplasmic and mitochondrial NAD + kinases

Nat Nanotech 2:577583

Khan N, Rahim SS, Boddupalli CS, Ghousunnissa S, Padma S, Pathak N, Thiagarajan D, Hasnain SE, Mukhopadhyay S

While many patients tolerate it well, it is important to be aware of potential risks, especially with repeated use