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Extended Activity: Due to reduced binding to IGF-binding proteins, IGF-1 LR3 may produce more prolonged receptor engagement than equivalent amounts of native IGF-1 in experimental systems, allowing for detailed study of dosetime relationships and cumulative effects on cell populations

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Schwrer, S., Vardhana, S

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The Keio University Animal Research Committee approved all animal procedures used in this study [12048-(3)]

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