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Some of the excess glutamate accumulate in synaptic clefts in HD would be carried away in the extracellular fluid, thus eventually causing a lowered glutamate content in striatal tissue
The differences in the predictive value of each of these catecholamines may well be due to their affinities for adrenoceptor sub-types

The NF-B pathway functions as a central pro-survival and pro-inflammatory transcription factor that promotes tumor progression by suppressing tumor suppressors such as phosphatase and tensin homolog (PTEN), thereby indirectly enhancing PI3K/AKT signaling and supporting cancer cell viability

Saudi J Biol Sci 28(9):48914899 Li H, Oh SH, Shin H-C, Suh M-W (2022) Intratympanic administration of dieckol prevents ototoxic hearing loss
