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Description
Most proposed mechanisms at the molecular level have only been observed in cell systems or animal models, but not confirmed in humans
Tkach, M
Animals were housed either individually (social isolation group) or in groups of 3-4 per cage (group-housed controls) under standardized laboratory conditions: 12-h light/dark cycle (lights on at 06:00), ambient temperature maintained at 20 C22 C, and relative humidity of 55%60%
When meals are consumed too close to bedtime, eaten sporadically, or spaced too far apart, this rhythm is disrupted
