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The anticonvulsant valproic acid (Depakene) interferes with L-carnitine biosynthesis in the liver and forms with L-carnitine a valproylcarnitine ester that is excreted in the urine

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Epigenetic DNA methylation changes associated with headache chronification: A retrospective case-control study

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PLoS Med.2006;3(11):e442

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-Lipoic acid dependent regeneration of ascorbic acid from dehydroascorbic acid in rat liver mitochondria

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