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Vulnerable populations, such as children, the elderly, individuals with pre-existing health conditions, and those from lower socioeconomic backgrounds, are disproportionately affected by PM exposure

Depletion of endogenous GSH sensitizes cells to cuproptosis, whereas GSH supplementation mitigates copper-induced proteotoxic stress 164,168

Irrespective of the discrepancy in global protein synthesis rates, granzyme B is highly translated at time points corresponding to both proliferating and nonproliferating effector T cells in vivo [16]

Clinical trials show tirzepatide produces greater weight loss than semaglutide in head-to-head studies, with some patients losing 20-25% of body weight