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You can get pernicious anemia if: You have an autoimmune disease that makes your immune system attack the cells in your stomach that produce intrinsic factor, a protein that helps your body absorb B12

Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation

Without enough B12, the body struggles to produce healthy red blood cells, which in turn reduces the oxygen-carrying capacity of the blood

[DOI] [PMC free article] [PubMed] [Google Scholar] 8
