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In a previous study on an omega GST from the saprophytic fungus Trametes versicolor , we showed that a deep H-site could be correlated with the ability of the GST protein to bind polyphenols like flavonoids ( APO (residues Val 159 to Gly 170 ) were refined in two conformations (Supplementary Figure S6)

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As we age, or as the body is exposed to more environmental stress, natural glutathione levels can decline, which is part of why IV supplementation has become so popular