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2020) and early growth for multiple antioxidants (Burguieres et al

In addition to inducing fatty liver, HFD also promotes systemic metabolic syndrome with insulin resistance and glucose intolerance

Clinical awareness expanded to include nonmotor symptoms, but early diagnosis and longitudinal care remained constrained in resourcelimited settings [52]

Tumors have evolved a unique microenvironment, and typically display a more acidic condition, hypoxia, overexpressed reactive oxygen species (ROS), and glutathione (GSH) owing to their rapid proliferation and metabolism (Zhou et al., 2018
