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In contrast, sensitive genotypes display erratic genome-wide hyper- and hypomethylation patterns that correlate with poor acclimation and yield loss, offering potential for actionable epiallele selection (Zhang et al., 2024a)

While these mechanisms suggest promising potential for KDs in overcoming therapeutic resistance, definitive clinical evidence is still being gathered through ongoing research

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For individuals who prefer a needle-free, painless delivery system, this makes them an appealing option