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The Active Role of Ca 2+ Ions in A-Mediated Membrane Damage

SIRT2 promotes the migration and invasion of gastric cancer through RAS/ERK/JNK/MMP-9 pathway by increasing PEPCK1-related metabolism

For example, in colon cancer cells (PC-3 cell line), at curcumin concentrations ranging from 0 to 50 M, treatment was associated with decreased phosphorylation of Akt kinase (Akt), mammalian target of rapamycin (mTOR), glycogen synthase kinase (GSK3), Forkhead box protein O1 (FOXO1), and other proteins (Yu et al., 2008)

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