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The pathophysiological effects of a lifestyle based on CHORD have been associated with a chronic high glycemic overload that leads to harmful metabolic consequences over time (Giugliano et al., 2018)

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body mass index (BMI) of 21.033.0 kg/m 2 , sedentary lifestyle (defined by Stanford questionnaire, Additional file 1: Table S1), maintain current dietary habits and activity levels, if taking supplements agree to maintain dosing regimen for at least one month prior to baseline and during the study, agree not to start any new supplements, give voluntary, written informed consent to participate

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