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Causes of Cyclic Vomiting Syndrome The exact cause of CVS is not fully understood, but the brain and gut share several biological mechanisms, including the role of serotonin

ERGO inhibited activities of HNMT in the mouse brain cytosol and recombinant human HNMT (rhHNMT) in a concentration-dependent manner (Fig

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Considering the multifactorial nature of TMAO generation, many strategies can be pursued to reduce the level of TMA/TMAO in patients with CVDs, such as lifestyle changes, use of antibiotics and functional foods, development of related inhibitors, and improvement of gut microbiota ( Supplementary Table 4 )