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This effect facilitates increased IGF-1 production, with potential benefits like improved body composition, bone mass, and cellular growth

doi: 10.1038/s41576-018-0059-1 93 RenC

Exogenous IGF-1 alleviates depression-like behavior and hippocampal mitochondrial dysfunction in high-fat diet mice

These will likely include approaches targeting both aberrant neuronal function, as well as pathological processes such as inflammation that may indirectly affect sensory systems