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In addition, endothelial cells can be activated by IL-1 and TNF- molecules, and activated endothelial cells can express and expose adhesion molecules, including p-selectin, e-selectin, and L-selectin within a few hours (Przykaza, 2021), which is more conducive to the rolling and adhesion of white blood cells

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Finally, due to space limitations, certain immunological markers, such as dendritic cell function or immunoglobulin production, were not extensively discussed

Due to the overlapping inhibitory profile of CD and Cyto D [65], caveolae, clathrin mediated or macropinocytotic pathways may participate in the 3-PLG uptake in brain endothelial cells