glutathione cancer review Glutathione-mediated nanomedicines for diagnosis and therapy Excessive glutathione intake contributes to

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All experiments were performed at 25 C in a buffer solution containing 20 mM HEPES (pH 7.0), 150 mM NaCl, and 1 mM DTT

358 Similarly, administration of metformin in cerebral ischemic stroke models alleviated oxidative stress-induced BBB damage, possibly through activation of the NRF2/ARE signaling pathway

Presence or absence of metal ions in the reaction mixture did not affect the enzyme activity

Next, two cell lines, DLD-1 (KRAS G13D/- ) and HT29 (BRAF V600E ), were used as models of intrinsic resistance to cetuximab, and Caco-2-CR was used as a model of acquired resistance to cetuximab for further study