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Description
Mercapturate pathway metabolites of sotorasib, a covalent inhibitor of KRAS(G12C), are associated with renal toxicity in the Sprague Dawley rat

Functionally, caspases involved in apoptosis have been subclassified into initiator (caspases 8, 9, and 10) and effector (caspases 3, 6, and 7) caspases, the initiator caspases are activated by proapoptotic signals and subsequently coordinate their activities to activate effector caspases (McIlwain et al., 2013)

C10H10N2 Every batch of 5-Amino-1MQ is sent to an accredited independent laboratory before it ships

10.1016/j.neurot.2025.e00600 14 ChenY.LuY.WangY.DingN.HuangZ.HuJ.et al (2025b)
