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[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Michael-Titus AT

Decreasing the liberation of glutamate from the glutathione cycle leads to decreased cortical neuron glutamate, while decreasing the utilization of glutamate increases total glutamate by about 25%

62 However, in a phase II randomized controlled trial, SAM neither reduced liver damage in patients with HCV cirrhosis nor improved the liver function

10.1371/journal.pone.0229438 5
