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elegans and Homo sapiens are able to translocate ER proteins for lysosomal eradication via macroautophagy via GRP78-IRE1 mediation of the UPRER and further recruitment of translocon Sec-62 (in worms, an orthologous C18E19.2) (Urban et al., 2025)
[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Valenti D., de Bari L., De Filippis B., Henrion-Caude A., Vacca R.A
Because their exact levels are not declared here, the saved review treats them as strong supporting peptides rather than a total peptide percentage claim
doi:10.1111/bph.13509
