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Recent advances in nanoparticle-based approaches for the treatment of brain tumors: opportunities and challenges
(ii) GC1 has a higher Km (~5 mM) for glutamate/H+, similar to the levels measured in intact mitochondria from the liver and kidney, whereas GC2 has a markedly lower Km (~0.26 mM) and shows low expression in many tissues [39]

Mature iron-sulphur clusters have been shown not to be affected by cobalt

However, acetaminophen inhibits both COX isoforms by acting on the peroxide site and reducing the amount of the PTGS oxidized form required for AA conversion [2,80,81]
