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Pinazo-DurnMDGallego-PinazoRGarca-MedinaJJZann-MorenoVNucciCDolz-MarcoRet al

Bancroft, J

The frequent onset of acute dose-dependent kidney injury, with the potential of leading to long-term renal damage, has limited its use and hampered adequate dosing regimens, increasing the risk of suboptimal plasma concentrations during treatment

This is despite the fact that as recently as 2013, research found that just three months of twice-daily carnitine and carbohydrate supplementation (80g carbs + 1.5g carnitine) was not only able to raise muscle carnitine levels significantly, but also increase the activity of genes in the muscles that are involved in stimulating fat burning during exercise (8)